Connective Tissue Diseases in the Skin

Neutrophilic Skin Lesions in Autoimmune Connective Tissue Diseases

The pathophysiology of neutrophilic dermatoses (NDs) and autoimmune connective tissue diseases (AICTDs) is incompletely understood. The association between NDs and AICTDs is rare; recently, however, a distinctive subset of cutaneous lupus erythematosus (LE, the prototypical AICTD) with neutrophilic histological features has been proposed to be included in the spectrum of lupus. The aim of our s...

Regulatory B cells in skin and connective tissue diseases.

While B cells are generally considered to be positive regulators of humoral immune responses due to their ability to differentiate into plasmablasts/plasma cells and produce antibodies, B cells also modulate immune responses through antigen presentation and cytokine secretion. Moreover, "regulatory B cells" that suppress immune responses have been recognized as an important new component of the...

A Histopathologic Study of Connective Tissue Diseases of Skin

Cutaneous involvement is a prominent feature in connective tissue disease and the skin lesions are extremely important in diagnosing and subclassifying patients with these conditions. Fifty cases of connective tissue diseases of skin were studied over a period of two years to analyze overlapping of histopathological features, possible transformation of one disease to the other and co-existing c...

The real connective tissue diseases.

689–90. 16 Corrao S, Salli L, Arnone S, Scaglione L, et al. Echodoppler abnormalities in patients with rheumatoid arthritis without clinically evident cardiovascular disease. Eur J Clin Invest 1996;26:293–7. 17 Slack D, Waller B. Acute congestive heart failure due to the arteritis of rheumatoid arthritis. Early diagnosis by endomyocardial biopsy. Angiology 1986;6:477–81. 18 Banks MJ, Flint EJ, ...

Connective tissue diseases.